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WEBINAR Hit discovery against epigenetic targets
14 december 2020 @ 16:00 - 16:45
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Presentation by:
Dr. Saman Honarnejad – Director Drug Discovery at Pivot Park Screening Centre
Topics:
- Trained immunity.
- The role of epigenetic targets in trained immunity.
- Hit discovery through ultra-High throughput screening of large libraries.
- Industry standard Hit-to-Lead (H2L) biological profiling frameworks.
Join us for this webinar in which we will focus on epigenetic targets:
• Center for Open Innovation in LEad Discovery (COILED) is a collaborative drug discovery program focused on epigenetic targets.
• Modulation of trained innate immunity for treatment of hyper-inflammation and immune deficiency-driven diseases like sepsis and cancer.
• ultra-High Throughput Screening (uHTS) campaign of 300,000 diverse set of compounds has led to the identification of 3 novel scaffolds (starting points) that progressed into Hit-to-Lead (H2L) phase.